WebThe binding of two transcription factors, BMAL1 (brain and muscle ARNT-like protein 1, also known as ARNTL, aryl hydrocarbon receptor nuclear translocator like) and CLOCK (Circadian Locomotor Output Cycles Kaput), positively regulate expression of a large number of “circadian clock genes (CCG)” by binding to E-box elements in promoters of ... WebJun 6, 2012 · Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis Mikhail Geyfman , Vivek Kumar , Qiang Liu , +8 , Rolando …
Brain and muscle Arnt-like 1 is a key regulator of myogenesis
Webbrain and muscle Arnt-like protein-1 (BMAL1; also referred to as MOP3 or Arnt3) and circadian locomotor output cycles kaput (CLOCK), play central roles [12–15]. BMAL1 and CLOCK form a heterodimer and drive transcription from E-box elements found in the promoters of circadian-responsive genes, including period (Per) 1 and cryptochrome (Cry). WebAug 18, 2013 · Brain and muscle aryl hydrocarbon receptor nuclear translocator-like protein-1 (BMAL1), one of the clock genes, is a transcription factor that plays central roles in the regulation of circadian … civil war gold found fbi
Effects of BMAL1 Manipulation on the Brain
WebSep 22, 2011 · A link between circadian rhythm and metabolism has long been discussed. Circadian rhythm is controlled by positive and negative transcriptional and translational feedback loops composed of several … WebFeb 1, 2015 · Interestingly, although the essential clock transcription activator, Brain and muscle Arnt-like 1 (Bmal1), participates in maintenance of muscle mass, little is known regarding its role in muscle growth and repair. In this report, we investigate the in vivo function of Bmal1 in skeletal muscle regeneration using two muscle injury models. … WebBRAIN AND MUSCLE ARNT-LIKE PROTEIN 1; BMAL1 TIC, MOUSE, HOMOLOG OF MEMBER OF PAS SUPERFAMILY 3; MOP3 CYCLE, DROSOPHILA, HOMOLOG OF HGNC Approved Gene Symbol: BMAL1. Cytogenetic location: 11p15.3 ... civil war gold fbi pennsylvania