Hif1a是什么基因
Web2 de ago. de 2024 · In human three paralogs of alpha subunit are known: HIF1A, EPAS1 (endothelial PAS domain-containing protein 1, also known as HIF2A) and HIF3A. 1, 5 Both, alpha and beta subunits are members of the basic helix-loop-helix Per-ARNT-Sim (bHLH-PAS) family of proteins. WebFigure 2. HIF1A protein in macrophages is elevated in hemophagocytic lymphohistiocytosis (HLH) mouse models. (A) Schematic diagram depicting lymphocytic choriomeningitis virus (LCMV)-infected Prf1 − / − HLH mouse model. Perforin-deficient (Prf1 − / −) mice were infected with or without LCMV-WE of 200 plaque-forming units (PFU) via intraperitoneal …
Hif1a是什么基因
Did you know?
WebSummary. HIF1 alpha antibody recognizes HIF1 alpha (HIF1a) protein, which is a subunit of the heterodimeric transcription factor hypoxia-inducible factor-1 (HIF-1). HIF-1 is a master regulator of homeostatic adaption to hypoxia (low oxygen supply) in various physiological and pathological conditions including normal development and cancer. WebHIF1 regulates the transcription of a broad range of genes that facilitate responses to the hypoxic environment, including genes regulating angiogenesis, erythropoiesis, cell cycle, metabolism, and apoptosis. The …
Web21 de mar. de 2024 · HIF1A (Hypoxia Inducible Factor 1 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF1A include Retinal Ischemia and Enchondromatosis, Multiple, Ollier Type . Among its related pathways are Signaling by PTK6 and Regulation of activated PAK-2p34 by proteasome mediated degradation . WebCatalog #. AM16708. Standard 5 nmol. Purification: HPLC In-Vivo Ready Standard. Size: 5 nmol 20 nmol 20 nmol 20 nmol 20 nmol 40 nmol 40 nmol 100 nmol 250 nmol 250 …
WebHypoxia-inducible factor 1 (HIF1) is a heterodimeric transcription factor that plays a critical role in the cellular response to hypoxia (1). The HIF1 complex consists of two subunits, HIF-1α and HIF-1β, which are basic … Web21 de mar. de 2024 · HIF1A-AS2 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path. Cytogenetic band: 14q23.2 by HGNC. 14q23.2 by Entrez …
Webhif1a （hypoxia inducible factor 1 alpha subunit） 该基因编码转录因子缺氧诱导因子-1（hif-1）的α亚单位，是由α亚单位和β亚单位组成的异二聚体。
Web3 de mar. de 2024 · Hypoxia-inducible factor 1 (HIF1) is a heterodimeric transcription factor, consisting of a constitutively expressed β-subunit (HIF1B) and a regulated α-subunit … nvme memory ssdWebBoth HIF1A and endothelial PAS domain protein 1 (EPAS1) are involved in the potentiation of INHA gene upregulation in cytotrophoblasts cultured under hypoxia. What Is Known Already During the in vitro differentiation of cytotrophoblasts into syncytiotrophoblasts under 21% O 2, INHA expression increases. nvme meaning ssdWeb25 de mar. de 2024 · We obtained femoral heads from Col2a1-Cre ERT2; Hif1a fl/fl (KO) and Hif1a fl/fl (Cntl) mice after tamoxifen treatment, and cultured them with or without IL … nvme memoryWeb26 de fev. de 2024 · Here, the authors show that HIFAL, the HIF1alpha antisense long non-coding RNA, and HIF1alpha form a positive feed-forward loop which is essential for … nvme lockdown commandWeb17 de jan. de 2024 · Increased HIF-1α expression in activated B cells. a Quantitative RT-PCR analyses of Hif1a and Hif2a in wild-type (WT) splenic B cells stimulated with … nvme micron 2450 mtfdkba512tfkWeb15 de nov. de 2024 · HIF1A-deficient cancer cells express a proinflammatory signature that is dependent on glycogen In order to explore the mechanism by which increased glycogen accumulation could contribute to HIF1A-independent tumor growth, we analyzed the signaling pathways upregulated in shHIF1A cells. nvme memory typesWeb9 de jul. de 2024 · Hypoxia-inducible factor 1α (HIF1A) is a principal regulator of hypoxia and is involved in multiple biological processes of antitumor immunity. Investigating the specific role of HIF1A in T-cell exhaustion in gliomas is an important issue, which could help to improve the efficacy of immunotherapy. nvme micron_3400_mtfdkba1t0tfh 1tb