Webb30 nov. 2014 · The results indicated that the activity of the synthetic coumarins depends upon the substituents present on the coumarin skeleton. Twenty-three (23) derivatives of coumarin (5-27) were synthesized and screened for their in vitro β- glucuronidase (E. coli) inhibitory activities. WebbOSI-027 (ASP4786, CERC 006, AEVI-006) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM in cell-free assays, and more …
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WebbThapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2 ... :2466-70. doi: 10.1073/pnas.87.7.2466. Authors O Thastrup 1 , P J Cullen, B K Drøbak, M R Hanley, A P Dawson. Affiliation 1 Department of Clinical Chemistry, University Hospital , Rigshospitalet, Copenhagen ... WebbH7, an inhibitor of protein kinase C, inhibits tumour cell division in mice bearing ascitic Ehrlich's carcinoma. We have previously shown that H7, an inhibitor of protein kinase … land for sale ralls county missouri
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